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NCT07285408: SARC-NMIBC

Sarcopenia and NMIBC Prognosis Study

Not yet recruiting Last updated 16 December 2025
What this trial tests

trial in Bladder Cancer Cell Transitional in 150 participants. Not yet recruiting.

Timeline
2 March 2026
Primary endpoint
12 July 2027
9 July 2029

Quick facts

Lead sponsorGeneral Hospital Sveti Duh
StatusNot yet recruiting
Study typeOBSERVATIONAL
Enrollment150
Start date2 March 2026
Primary completion12 July 2027
Estimated completion9 July 2029

Conditions studied

Sponsor

General Hospital Sveti Duh

Who can join

18 and older, any sex, with Bladder Cancer Cell Transitional. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this observational study is to evaluate whether body composition abnormalities (sarcopenia, myosteatosis, and obesity) and nutritional status influence the risk of recurrence and progression in adult patients with non-muscle-invasive bladder cancer (NMIBC). The main questions it aims to answer are: Do sarcopenia, myosteatosis, obesity, or malnutrition increase the likelihood of NMIBC recurrence and progression? Can clinical, laboratory, and CT-derived body composition parameters serve as predictive biomarkers that improve individualized risk stratification? Participants will undergo routine clinical and radiologic assessments, including: * completion of the SARC-F and NRS nutritional screening questionnaires * anthropometric measurements (BMI, waist circumference) * laboratory evaluation including serum albumin and testosterone * CT-based assessment of skeletal muscle index (SMI) and muscle density (SMD) * standard TURBT and structured follow-up with cystoscopy, cytology, imaging, and clinical evaluations to document recurrence and progression.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other General Hospital Sveti Duh trials

Trials by the same sponsor.

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Data sources for this page

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