Last reviewed · How we verify
NCT07278167
Analysis of Risk Factors and Prognostic Predictive Value in Sepsis Patients With Nutritional Risk
trial testing Retrospective data analysis, no intervention in Sepsis in 400 participants. Completed in 1 July 2025.
1 July 2025
Quick facts
| Lead sponsor | The Affiliated Hospital of Inner Mongolia Medical University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 400 |
| Start date | 1 March 2025 |
| Primary completion | 1 July 2025 |
| Estimated completion | 1 July 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Retrospective data analysis, no intervention
Conditions studied
- Sepsis — all drugs for Sepsis →
- Nutritional Risk — all drugs for Nutritional Risk →
Sponsor
The Affiliated Hospital of Inner Mongolia Medical University
Who can join
18 and older, any sex, with Sepsis or Nutritional Risk. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sepsis is a common critical illness in intensive care units, characterized by systemic inflammatory response, immune dysfunction, microcirculatory issues, and multi-organ failure. These factors lead to high mortality rates and poor prognoses for patients. Nutritional risk is a significant complication in patients with sepsis, with a prevalence of 38% - 78. Sepsis-induced hypermetabolism and hypercatabolism result in increased energy expenditure and accelerated protein breakdown in affected patients, which subsequently exacerbates the risk of malnutrition. Malnutrition weakens immune function, reduces resistance to infections, and impairs immune regulation in sepsis patients. It worsens organ dysfunction, prolongs ICU hospitalization, and increases morbidity and mortality rates. Early identification and intervention for potential risk factors in patients with sepsis, particularly those with nutritional risk, is crucial for enhancing their prognosis. There is a notable lack of sensitive indicators for assessing the prognosis of sepsis patients at nutritional risk. Recent studies have begun exploring physical assessment measures in ICU settings as accessible and noninvasive tools for evaluation. This study aims to investigate the predictive value of nutritional laboratory indicators and physical measurements regarding the 28-day outcomes of ICU patients with sepsis and nutritional risk, providing a foundation for early clinical intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Predictive value of calf circumference, prealbumin, and serum calcium for 28-day mortality in male sepsis patients with nutritional risk: a retrospective study.
Luan H, Liu Q, Fan H, Guo Y, et al · · 2026 · PMID 42180602 · DOI 10.7717/peerj.21316
Verify or expand the search:
- PubMed search for NCT07278167
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sepsis
Currently open trials in the same condition.
- NCT07507877 — Infraclavicular Axillary Vein Collapsibility Index as a Predictor of Fluid Responsiveness · recruiting
- NCT07154615 — Assessing Immune Dysfunction in Sepsis · recruiting
- NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
- NCT07351344 — African Survey on Sepsis Knowledge (ASK) · recruiting
- NCT07448805 — Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07278167 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Affiliated Hospital of Inner Mongolia Medical University
- Last refreshed: 11 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07278167.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing