Who is sponsoring AISstdy?

AISstdy is sponsored by Haseki Training and Research Hospital.

What condition does AISstdy study?

AISstdy studies Acute Ischemic Stroke, Hypertensive Crisis.

What drugs are being tested in AISstdy?

Interventions: nicardipine intravenous, labetalol intravenous.

What is the status of AISstdy?

AISstdy is currently COMPLETED.

Last reviewed 2025-12-11 · How we verify

Nicardipine vs. Labetalol (AISstdy)

NCT07277283 PHASE4 COMPLETED

In this ED-based study, the investigators compared the time to reach target blood pressure (BP) between hypertensive patients with acute ischemic stroke (AIS) undergoing intravenous (IV) thrombolysis and/or mechanical thrombectomy who received IV nicardipine versus labetalol. Additionally, the investigators evaluated the rate of early neurological improvement (ENI), length of hospital stay (LOS), in-hospital mortality, and adverse event profiles between the two treatment groups.

Details

Lead sponsor	Haseki Training and Research Hospital
Phase	PHASE4
Status	COMPLETED
Enrolment	34
Start date	Sat Feb 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Aug 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Acute Ischemic Stroke
Hypertensive Crisis

Interventions

nicardipine intravenous
labetalol intravenous

Countries

Turkey (Türkiye)