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Perioperative Tamsulosin for Treating Voiding Dysfunction Following Prostate Biopsy

NCT07276919 PHASE4 NOT_YET_RECRUITING

The goal of this clinical trial is to learn if the drug Tamsulosin Hydrochloride works to treat urination difficulties after a prostate biopsy in men.The main questions it aims to answer are: * Does Tamsulosin Hydrochloride lower the rate of Acute Urinary Retention (inability to urinate) after a prostate biopsy? * Does Tamsulosin Hydrochloride improve participants' urination symptoms, quality of life, urine flow rate, and post-void residual urine volume? Researchers will compare the drug group to a control group (receiving no preventive medication) to see if Tamsulosin Hydrochloride works to prevent urination problems. Participants will: * Be randomly assigned to either take Tamsulosin Hydrochloride or receive no preventive medication. * If in the drug group, take one capsule of Tamsulosin Hydrochloride every night, starting 3 days before the biopsy and continuing until 6 days after the biopsy (10 doses total). * Undergo a standard prostate biopsy procedure (either through the rectum or perineum). * Return to the clinic 7 days after the biopsy for a follow-up checkup, which will include questions about their symptoms (IPSS and QoL scores) and tests to measure urine flow and bladder emptying.

Details

Lead sponsorPeking University First Hospital
PhasePHASE4
StatusNOT_YET_RECRUITING
Enrolment1844
Start dateSun Feb 01 2026 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionSat Jan 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

China