Who is sponsoring NCT07275177?

NCT07275177 is sponsored by Universidad Autónoma Benito Juárez de Oaxaca.

What condition does NCT07275177 study?

NCT07275177 studies Obesity (Disorder), Obesity, Sarcopenia, Sarcopenia in Elderly, Sarcopenic Obesity, Vitamin D Deficiency, Vitamin D 25-Hydroxylase Deficiency, Muscle Strengh, Muscle Mass, Aging, Older Adults (65 Years and Older), Functional Decline, Age-Related Loss of Skeletal Muscle Mass, Muscle Weakness.

What drugs are being tested in NCT07275177?

Interventions: Vitamin D, Vitamin D placebo.

What is the status of NCT07275177?

NCT07275177 is currently COMPLETED.

Last reviewed 2025-12-10 · How we verify

Effect of Vitamin D on Body Composition and Functionality of Older Adults

NCT07275177 NA COMPLETED

Older adults with obesity often experience a gradual loss of muscle mass and muscle strength, a condition sometimes described as sarcopenic obesity. This combination increases the risk of falls, disability, functional decline, and metabolic complications. Low levels of vitamin D are common in older adults and may contribute to reduced muscle function and poorer physical performance. This study is designed to evaluate whether taking 10,000 International Units (IU) per day of vitamin D3 for 12 weeks can improve muscle strength and muscle mass in older adults with obesity living in southern Mexico. The study will also examine whether vitamin D3 supplementation influences body composition, physical performance, and serum levels of 25-hydroxyvitamin D. Participants will complete assessments at the beginning and at the end of the 12-week period. These assessments include measurements of muscle strength, skeletal muscle mass, body fat percentage, and indicators of physical performance such as the Short Physical Performance Battery (SPPB). Additional measures of body composition and anthropometry, such as body mass index, waist circumference, and related indices, will also be recorded. Blood samples will be analyzed to determine vitamin D status. All participants will receive daily oral vitamin D3 (cholecalciferol) throughout the 12-week intervention. The goal of the study is to understand whether improving vitamin D status can have a positive effect on muscle health and physical function in older adults with obesity. The results from this research may help guide future strategies to prevent or reduce functional decline related to low muscle mass in older adults with obesity, particularly in rural regions of Mexico where vitamin D deficiency is common.

Details

Lead sponsor	Universidad Autónoma Benito Juárez de Oaxaca
Phase	NA
Status	COMPLETED
Enrolment	29
Start date	Tue Jan 09 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sat Nov 09 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Obesity (Disorder)
Obesity
Sarcopenia
Sarcopenia in Elderly
Sarcopenic Obesity
Vitamin D Deficiency
Vitamin D 25-Hydroxylase Deficiency
Muscle Strengh
Muscle Mass
Aging

Interventions

Vitamin D
Vitamin D placebo

Countries

Mexico