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NCT07268846: POSBIO-CRC
Use of Preoperative Postbiotic Supplementation in Colorectal Cancer Surgery
NA trial testing Postbiotic in Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma) in 164 participants. Currently enrolling.
1 June 2027
Quick facts
| Lead sponsor | AC Camargo Cancer Center |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 164 |
| Start date | 1 June 2025 |
| Primary completion | 1 June 2027 |
| Estimated completion | 1 June 2027 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Postbiotic — full drug profile →
- Placebo
Conditions studied
- Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma) — all drugs for Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma) →
Sponsor
AC Camargo Cancer Center — full company profile →
Who can join
18 and older, any sex, with Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The treatment of colorectal cancer, in the absence of metastases, is primarily based on surgical removal. Colorectal surgery, which involves resecting part of the intestine and restoring intestinal continuity, carries a risk of complications. This study aims to evaluate whether oral supplementation with a postbiotic at a dose of 900 mg for 7 days prior to surgery reduces the rate of postoperative complications.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Postbiotics as Emerging Strategy Targeting Obesity- and Aging-Related Breast Cancer-Prospects in Prophylaxis and Therapy.
Wasiak J, Oszajca KA, Szemraj J, Witusik-Perkowska M. · · 2026 · PMID 42073437 · DOI 10.3390/life16040628
Verify or expand the search:
- PubMed search for NCT07268846
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT07527286 — The Effects of a Postbiotic Supplement on Biomarkers of Gut Health · completed
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Other recruiting trials for Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
Currently open trials in the same condition.
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Other AC Camargo Cancer Center trials
Trials by the same sponsor.
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- NCT06793137 — Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer · Phase 2 · recruiting
- NCT06472388 — Everolimus 5 mg vs 10 mg/Daily for Patients With Neuroendocrine Tumors · Phase 2 · recruiting
- NCT06207487 — Evaluation of Herpes Zoster Characteristics and Costs in Cancer Population. · unknown
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07268846 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by AC Camargo Cancer Center
- Last refreshed: 8 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07268846.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing