Who is sponsoring NCT07267299?

NCT07267299 is sponsored by Southern College of Optometry.

What condition does NCT07267299 study?

NCT07267299 studies Dry Eye, Eye Diseases, Chronic Dry Eye.

What drugs are being tested in NCT07267299?

Interventions: acoltremon 0.003%.

What is the status of NCT07267299?

NCT07267299 is currently NOT_YET_RECRUITING.

Last reviewed 2025-12-05 · How we verify

Switching From Restasis to TRYPTYR

NCT07267299 PHASE4 NOT_YET_RECRUITING

Switching to acoltremon 0.003% will significantly improve the signs and symptoms of participants who were being treated with Restasis at 28 days post-treatment compared to baseline. Dry eye disease (DED) is a prevalent condition that commonly affects patients of working age in addition to the elderly. DED is a complex condition that results in ocular symptoms such as dryness and burning and signs such as decreased tear production (aqueous deficient DED) or increased tear evaporation (evaporative DED). Unfortunately, there is not a perfect correlation between DED signs and symptoms, which makes diagnosis and timely treatment challenging.

Details

Lead sponsor	Southern College of Optometry
Phase	PHASE4
Status	NOT_YET_RECRUITING
Enrolment	100
Start date	Mon Dec 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri May 15 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Dry Eye
Eye Diseases
Chronic Dry Eye

Interventions

acoltremon 0.003%