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NCT07261540: STASFP-OA
Bilateral Knee Strength Asymmetry and Functional Performance in Older Women With Osteoarthritis
trial testing Isokinetic Strength Testing in Knee Osteoarthristis in 20 participants. Completed in 1 June 2025.
5 May 2025
Quick facts
| Lead sponsor | Kocaeli Sağlık ve Teknoloji Üniversitesi |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 1 April 2025 |
| Primary completion | 5 May 2025 |
| Estimated completion | 1 June 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Isokinetic Strength Testing
Conditions studied
- Knee Osteoarthristis — all drugs for Knee Osteoarthristis →
- Postmenopausal Women — all drugs for Postmenopausal Women →
- Functional Performance — all drugs for Functional Performance →
- Isokinetic Test — all drugs for Isokinetic Test →
Sponsor
Kocaeli Sağlık ve Teknoloji Üniversitesi
Who can join
50 and older, female only, with Knee Osteoarthristis or Postmenopausal Women. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Osteoarthritis (OA) is a degenerative joint disease that primarily affects the knees and becomes more prevalent with age. In individuals over 50, particularly those with bilateral knee osteoarthritis, it leads to chronic pain, limited mobility, and functional decline. This condition worsens due to muscle strength imbalances, especially in the quadriceps and hamstrings. These imbalances are triggered by pain, joint instability, and cartilage damage, which negatively impact muscle strength and coordination. In women, these asymmetries are more pronounced, increasing the risk of functional decline. Recent studies highlight the significant role of strength asymmetry in functional limitations, affecting balance, gait, and daily activities. This study aims to investigate the impact of bilateral quadriceps and hamstring strength asymmetries on dynamic balance, gait efficiency, and functional mobility in older women with bilateral knee osteoarthritis. The study aims to examine the effects of bilateral strength asymmetries in the knee extensors and flexors on dynamic balance, gait efficiency, and overall mobility in older women with bilateral knee osteoarthritis. We hypothesize that greater strength asymmetry will be associated with impaired dynamic balance, reduced gait efficiency, and decreased functional mobility.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07261540
- Europe PMC full search
- ASCO Meeting Library
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Related trials
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Trials testing the same drug.
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Other recruiting trials for Knee Osteoarthristis
Currently open trials in the same condition.
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07261540 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kocaeli Sağlık ve Teknoloji Üniversitesi
- Last refreshed: 3 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07261540.
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