NCT07261462

Oropharyngeal and Trunk Muscle Interactions After Stroke

Completed NA Last updated 9 December 2025

What this trial tests

NA trial testing Exercise in Stroke in 12 participants. Completed in 25 December 2022.

Timeline

1 February 2022

Primary endpoint
1 December 2022

25 December 2022

Quick facts

Lead sponsor	Necmettin Erbakan University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	12
Start date	1 February 2022
Primary completion	1 December 2022
Estimated completion	25 December 2022
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Exercise

Conditions studied

• Stroke — all drugs for Stroke →

Sponsor

Necmettin Erbakan University

Who can join

Adults 18 to 80, any sex, with Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background:This study aimed to investigate the effects of a short-term tongue-jaw-back isometric exercise program on these muscle groups and their interrelationships in the post-stroke period.

Methods: Twelve post-stroke patients were included in the study. A 14-day exercise program, consisting of two daily sessions targeting the tongue, jaw, and back muscles, was administered. Anterior and posterior tongue muscles, jaw muscles, and back muscle strength were assessed before and after the exercise program. Tongue pressure was measured using the Iowa Oral Performance Instrument (IOPI), chewing strength with a hand-held dynamometer, and back strength with a stabilizing pressure biofeedback unit.

Results: After the 14-day isometric exercise program, anterior tongue strength (p = 0.025), posterior tongue strength (p = 0.021), and back muscle strength (p = 0.005) showed significant increases compared to pre-treatment values. No significant change was observed in jaw strength (p = 0.475). Spearman correlation analysis revealed no significant relationships between tongue muscles and jaw or back muscles before treatment, and simple correlations after treatment also did not reach significance. However, partial correlation analysis showed that the relationship between tongue muscles was significantly influenced by jaw strength (p = 0.040) and back strength (p = 0.038) after the intervention.

Conclusions: Short-term isometric exercises targeting tongue, jaw, and back muscles in post-stroke patients effectively increased tongue and back muscle strength and enhanced the synergistic relationship among these muscle groups.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. The Effects of a Short-Term Isometric Exercise Program Targeting Tongue, Jaw, and Trunk Muscles on Muscle Strength and Synergistic Relationships in Post-Stroke Patients: A Single-Group Pre-Post Study
   Yılmaz NA, Küçükşen S. · · 2026 · DOI 10.21203/rs.3.rs-7751845/v1