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NCT07256028: IAA-EED
Indispensable Amino Acids Bioavailability in Children With Environmental Enteropathy Dysfunction (IAA-EED)
NA trial testing Indispensable amino acids supplemntation in Environmental Enteric Dysfunction in 40 participants. Not yet recruiting.
31 March 2026
Quick facts
| Lead sponsor | Morocco's National Centre for Energy, Sciences and Nuclear Techniques |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 40 |
| Start date | 10 December 2025 |
| Primary completion | 31 March 2026 |
| Estimated completion | 31 July 2026 |
| Sites | 1 location across Morocco |
Drugs / interventions tested
- Indispensable amino acids supplemntation
- Without Indispensable amino acids supplementation
Conditions studied
- Environmental Enteric Dysfunction — all drugs for Environmental Enteric Dysfunction →
Sponsor
Morocco's National Centre for Energy, Sciences and Nuclear Techniques
Who can join
Adults 18 Months to 36 Months, any sex, with Environmental Enteric Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In Morocco, large efforts have been made to enhance nutritional status and health conditions of children. Accordingly, stunting was reduced and the prevalence of stunting have decreased from 28,6% in 1987 to 14,9% in 2011. Many factors, including improved nutrition, have influenced this decrease, and are reinforced to maintain this low prevalence of stunting. Of interest, quality diet, specifically with reference to its protein quality, has contributed to improve the nutritional status of the Moroccan population. However, infectious diseases are still important and in some areas many children are of high risk to develop EED that alter intestinal permeability and microbial translocation, and lead to systemic inflammation. During childhood, protein supply is of a great interest and indigestibility of these proteins and/or malabsorption of indispensable amino acids will affect children growth and many physiological and cognitive functions. This project was planned to assess indispensable amino acids during EED and to to assess the impact of some interventions (amino acids supplementation / medical treatment) on the nutritional status of children. This study will be carried out according to a trilogy of close collaboration between CNESTEN, Pr Claire Gaudichon from AgroParisTech (France) who will provide technical assistance and scientific accompaniment during the progress of the project, she will also participate in the data analysis, exploitation and valorization of results and the department of Pediatric Hepatology Gastroenterology and Nutrition-P III at the Children's Hospital in Rabat.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Impact of indispensable amino acid supplementation on gut function in children at high risk of environmental enteropathy: protocol for an international coordinated group of randomised controlled trials.
Lee GO, Owino V, Baquiran AFP, Pasanna RM, et al · · 2026 · PMID 42031499 · DOI 10.1136/bmjopen-2025-105456
Verify or expand the search:
- PubMed search for NCT07256028
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Environmental Enteric Dysfunction
Currently open trials in the same condition.
- NCT07195006 — Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories · recruiting
- NCT05501470 — Probiotic For the Improvement of Environmental Enteropathy in Pregnant Women in Senegal · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07256028 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Morocco's National Centre for Energy, Sciences and Nuclear Techniques
- Last refreshed: 1 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07256028.
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