Last reviewed · How we verify
NCT07253155
Probiotics Use and Preventing Gastrointestinal Symptoms in People Living With Overweight and Obesity.
NA trial testing Probiotic Arm in Gut Inflammation in 100 participants. Enrolling by invitation.
1 September 2028
Quick facts
| Lead sponsor | University of Ulster |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 14 October 2025 |
| Primary completion | 1 September 2028 |
| Estimated completion | 1 September 2028 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Probiotic Arm — full drug profile →
- Placebo Arm
Conditions studied
- Gut Inflammation — all drugs for Gut Inflammation →
- Overweight and Obese Volunteers — all drugs for Overweight and Obese Volunteers →
Sponsor
University of Ulster
Who can join
18 and older, any sex, with Gut Inflammation or Overweight and Obese Volunteers. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Inflammatory bowel disease (IBD) affects over 6.8 million people worldwide, with current treatments often causing side effects and poor patient compliance. Dysbiosis of gut microbiota is a key factor, and while probiotics are considered safe and beneficial, conventional strains fail to function effectively during active inflammation due to high iron levels in the gut. Streptococcus thermophilus (FX856), unlike traditional probiotics, can thrive in this iron-rich environment, promoting mucosal healing. A 2-way crossover intervention study will be conducted with FX856 supplementation in overweight and obese individuals who often exhibit mild gut inflammation by measuring faecal calprotectin and systemic inflammatory markers.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07253155
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06910397 — The Effect of Probiotics on Gums Health and Bad Breath · NA · completed
- NCT07520422 — Bacillus Coagulans Based Product in IBS-Diarrhea · NA · completed
Other University of Ulster trials
Trials by the same sponsor.
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- NCT06914804 — Stomasense: A New Route to the Proactive Detection and Management of Leaks Within Ostomy Pouches · NA · enrolling by invitation
- NCT06921811 — Bioavailability From Chickpea Meals in Ileostomists? · NA · enrolling by invitation
- NCT06729229 — The YOU-Fish Study: Fish and Omega 3 Supplementation in Young Adults · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07253155 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Ulster
- Last refreshed: 28 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07253155.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing