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NCT07250503
Compare the Difference in Occlusal Force Distribution and Denture Retention Using 2 Different Denture Base Materials in Implant Retained Overdenture
NA trial testing Conventional acrylic resin denture in Edentulous Alveolar Ridge In Mandible in 24 participants. Participants enrolled and being followed up; not accepting new ones.
1 January 2026
Quick facts
| Lead sponsor | Al-Azhar University |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 1 September 2024 |
| Primary completion | 1 January 2026 |
| Estimated completion | 1 February 2026 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Conventional acrylic resin denture
- Flexible resin denture
Conditions studied
- Edentulous Alveolar Ridge In Mandible — all drugs for Edentulous Alveolar Ridge In Mandible →
- Complete Edentulism — all drugs for Complete Edentulism →
- Dental Implant — all drugs for Dental Implant →
- Attachments — all drugs for Attachments →
Sponsor
Al-Azhar University
Who can join
Adults 60 to 70, any sex, with Edentulous Alveolar Ridge In Mandible or Complete Edentulism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The global increase in the aging population has led to a rise in total edentulism, which remains a major public health concern. two-implant-retained mandibular overdentures have been regarded as the standard of care, offering superior retention, stability, comfort, and masticatory efficiency compared to conventional dentures. Among available attachment systems-bar, ball, stud, and magnet-the Equator attachment has gained popularity due to its low vertical profile, suitability for limited inter-occlusal space, and ease of handling. Assessment of masticatory performance and occlusal balance can be objectively measured using devices such as bite force analyzers and the computerized T-Scan system, which quantifies occlusion and disocclusion times. Conventional heat-cured polymethyl methacrylate (PMMA) remains the most widely used denture base material; however, it has mechanical and biological limitations. Flexible denture base materials have been introduced to overcome these drawbacks by enhancing adaptation, distributing occlusal loads more evenly, and improving comfort and retention.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07250503
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Related trials
Other trials of Conventional acrylic resin denture
Trials testing the same drug.
- NCT07271641 — A Study Comparing Two Different Denture Base Materials in Implant Retained Overdentures · NA · completed
Other recruiting trials for Edentulous Alveolar Ridge In Mandible
Currently open trials in the same condition.
- NCT06723678 — Evaluation of Bone Changes Around Implants in Patients Treated With All on Four · NA · recruiting
Other Al-Azhar University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07250503 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Al-Azhar University
- Last refreshed: 26 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07250503.
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