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NCT07249814
Comparison of Fractionated Versus Bolus Administration of Different Doses of Hyperbaric Bupivacaine Combined With Opioids in Spinal Anesthesia for Caesarean Section
NA trial testing Fractionated anesthesia in Spinal Anesthesia for Cesarean Section in 99 participants. Completed in 15 June 2025.
15 June 2025
Quick facts
| Lead sponsor | Bogomolets National Medical University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 99 |
| Start date | 30 June 2024 |
| Primary completion | 15 June 2025 |
| Estimated completion | 15 June 2025 |
| Sites | 1 location across Ukraine |
Drugs / interventions tested
- Fractionated anesthesia
- Bolus anesthesia
Conditions studied
- Spinal Anesthesia for Cesarean Section — all drugs for Spinal Anesthesia for Cesarean Section →
Sponsor
Bogomolets National Medical University
Who can join
Adults 18 to 50, female only, with Spinal Anesthesia for Cesarean Section. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aimed to compare the effectiveness and safety of fractionated versus bolus administration of different doses of hyperbaric bupivacaine (0.06 and 0.07 mg/cm height) combined with opioids in spinal anesthesia for cesarean section, with detailed evaluation of maternal hemodynamic effects, block characteristics and side effects.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Comparison of fractionated versus bolus administration of different doses of hyperbaric bupivacaine combined with opioids in spinal anesthesia for caesarean section - a prospective, randomized, participant-blind clinical trial.
Kuchyn I, Bielka K, Nimkovych R, Sirenko I. · · 2026 · PMID 41947048 · DOI 10.1186/s12871-026-03813-z -
Comparison of Fractionated Versus Bolus Administration of Different Doses of Hyperbaric Bupivacaine Combined With Opioids in Spinal Anesthesia for Caesarean Section – A Prospective, Randomized, Single Blind Clinical Trial
Kuchyn I, Bielka K, Nimkovych R, Sirenko I. · · 2025 · DOI 10.21203/rs.3.rs-7847370/v1
Verify or expand the search:
- PubMed search for NCT07249814
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Spinal Anesthesia for Cesarean Section
Currently open trials in the same condition.
- NCT07322419 — Hemodynamics During Cesarean Delivery Under Spinal Anesthesia With Norepinephrine Versus Ephedrine · Phase 4 · recruiting
Other Bogomolets National Medical University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07249814 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bogomolets National Medical University
- Last refreshed: 25 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07249814.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing