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Cross-linked Hyaluronic Acid in Knee Osteoarthritis
Knee Osteoarthritis (Knee OA) leads to pain and loss of function, especially in recreational athletes. While hyaluronic acid (HA) injections are a common part of conservative treatment, comparative data on the efficacy of straight-chain (ST-HA) versus cross-linked (CL-HA) formulations remain limited. Therefore, the aim of this study was to compare the 6-month efficacy of a single dose of CL-HA versus two doses of ST-HA regarding pain, stiffness, and joint function in recreational athletes aged 50-70 with Kellgren-Lawrence grade 2-3 Knee OA refractory to pharmacological treatment.
Details
| Lead sponsor | Istanbul Medipol University Hospital |
|---|---|
| Status | COMPLETED |
| Enrolment | 88 |
| Start date | Sat Jan 02 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sat May 31 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Knee Osteoarthritis (Knee OA)
Interventions
- Straight-bonded hyaluronic acid
- cross-linked hyaluronic acid
Countries
Turkey (Türkiye)