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NCT07240077: BLESS
Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia
Phase 4 trial testing Beta-lactam monotherapy in Bacteremia in 165 participants. Not yet recruiting.
31 December 2027
Quick facts
| Lead sponsor | Mahidol University |
|---|---|
| Phase | Phase 4 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 165 |
| Start date | 1 January 2026 |
| Primary completion | 31 December 2027 |
| Estimated completion | 31 December 2028 |
| Sites | 4 locations across Thailand |
Drugs / interventions tested
- Beta-lactam monotherapy — full drug profile →
- Beta-lactam plus levofloxacin combination therapy — full drug profile →
Conditions studied
- Bacteremia — all drugs for Bacteremia →
- Streptococcus Infection — all drugs for Streptococcus Infection →
Sponsor
Mahidol University
Who can join
18 and older, any sex, with Bacteremia or Streptococcus Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A double-blind randomized controlled trial comparing beta-lactam plus levofloxacin versus beta-lactam monotherapy for the treatment of Streptococcal bacteremia
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07240077
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07240077 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mahidol University
- Last refreshed: 20 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07240077.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing