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NCT07238738
Comparison Between Modified Periosteal Inhibition (MPI) and Flapless Immediate Implant Placement
NA trial testing Immediate implant placement via flapless approach in Non-restorable Posterior Teeth in 30 participants. Not yet recruiting.
1 December 2026
Quick facts
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 December 2025 |
| Primary completion | 1 December 2026 |
| Estimated completion | 1 January 2027 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Immediate implant placement via flapless approach
- Immediate implant placement in conjunction with modified periosteal inhibition technique using collagen sponge in the gap distance
- Immediate implant placement in conjunction with modified periosteal inhibition technique using cortico-cancellous bone allograft in the gap distance
Conditions studied
- Non-restorable Posterior Teeth — all drugs for Non-restorable Posterior Teeth →
- Thin Buccal Bone Plate — all drugs for Thin Buccal Bone Plate →
- Buccal Bone Fenestraion — all drugs for Buccal Bone Fenestraion →
Sponsor
Mansoura University
Who can join
Adults 20 to 50, any sex, with Non-restorable Posterior Teeth or Thin Buccal Bone Plate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To clinically and radiographically assess the impact of the modified periosteal inhibition (MPI) technique, applied during immediate post-extraction implant placement, on alveolar bone dimensional changes, in comparison to the conventional flapless immediate implant approach.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07238738
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07238738 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mansoura University
- Last refreshed: 26 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07238738.
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