NCT07237971: CAIR

Cocreating Action to Improve Rationality in the Health System

Recruiting now NA Last updated 2 December 2025

What this trial tests

NA trial testing Cocreation process in Health-Related Quality-of-Life in 4,000 participants. Currently enrolling.

Timeline

21 October 2025

Primary endpoint
1 April 2029

1 April 2029

Quick facts

Lead sponsor	Universidad Miguel Hernandez de Elche
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	4,000
Start date	21 October 2025
Primary completion	1 April 2029
Estimated completion	1 April 2029
Sites	2 locations across Spain

Drugs / interventions tested

• Cocreation process

Conditions studied

• Health-Related Quality-of-Life — all drugs for Health-Related Quality-of-Life →
• Social Capital — all drugs for Social Capital →
• Health Literacy — all drugs for Health Literacy →
• Community Based Participatory Research — all drugs for Community Based Participatory Research →

Sponsor

Universidad Miguel Hernandez de Elche — full company profile →

Who can join

18 and older, any sex, with Health-Related Quality-of-Life or Social Capital. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Despite widespread recognition of social, economic, or environmental health determinants, health action remains heavily dominated by individual-level solutions (e.g., medication, patient counselling, vaccination). This study aims to stimulate changes in health system functioning by demonstrating how the cocreation of actions to address psychological well-being, cardiovascular health, and antimicrobial resistance from within the community can alleviate the burden on primary care services, reduce medicalisation and increase health equity.

The scientific approach uses mixed methods and incorporates theory from multiple disciplines. This study will appraise how the current system addresses psychological well-being, cardiovascular (CV) health, and rational use of antibiotics using a population survey, a survey of patients collecting their medication at community pharmacies, aggregate health service indicators on medication consumption and primary care consultations, and qualitative methods exploring stakeholders' perceptions.The investigators will undertake community-based participatory research to engage citizen scientists in the cocreation of community-led actions to promote psychological well-being, CV health, and prevent antimicrobial resistance. The design, implementation, and evaluation of the actions will apply an assets-based approach and apply theories and frameworks from implementation science in an iterative manner over 3 years. Finally, the impact of the cocreated actions will be analysed, considering effectiveness and broader contextual issues such as initiative adoption, implementation, and maintenance. The investigators will use a before-after comparison of survey indicators, an interrupted time-series analysis of health service data and qualitative analysis.

The goal is to demonstrate how the integration of community action with attention to the social determinants of health, can lead to a more rational approach to health care and ultimately improve health and health equity.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.