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NCT07237555
CVL Risk After Severe Glaucoma Surgery
trial in Severe-stage Glaucoma (Mean Deviation ≤ -20 dB) in 523 participants. Participants enrolled and being followed up; not accepting new ones.
26 November 2025
Quick facts
| Lead sponsor | Gangnam Severance Hospital |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 523 |
| Start date | 27 November 2024 |
| Primary completion | 26 November 2025 |
| Estimated completion | 26 November 2026 |
| Sites | 1 location across South Korea |
Conditions studied
- Severe-stage Glaucoma (Mean Deviation ≤ -20 dB) — all drugs for Severe-stage Glaucoma (Mean Deviation ≤ -20 dB) →
Sponsor
Gangnam Severance Hospital
Who can join
Eligibility, any sex, with Severe-stage Glaucoma (Mean Deviation ≤ -20 dB). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This retrospective cohort study analyzes risk factors for central visual loss (CVL) after severe-stage glaucoma surgery. The primary hypothesis is that 1) visual prognosis is determined primarily by early postoperative intraocular pressure (IOP) stability rather than surgical choice, and 2) the nature of risk (hypotony vs hypertension) is modified by baseline visual reserve. We analyzed outcomes in 523 patients with severe-stage glaucoma who underwent trabeculectomy or Ahmed glaucoma valve (AGV) implantation, focusing on the dichotomous risk profile stratified by baseline visual acuity.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07237555
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07237555 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gangnam Severance Hospital
- Last refreshed: 20 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07237555.
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