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NCT07237555

CVL Risk After Severe Glaucoma Surgery

Active, enrolled Last updated 20 November 2025
What this trial tests

trial in Severe-stage Glaucoma (Mean Deviation ≤ -20 dB) in 523 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
27 November 2024
Primary endpoint
26 November 2025
26 November 2026

Quick facts

Lead sponsorGangnam Severance Hospital
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment523
Start date27 November 2024
Primary completion26 November 2025
Estimated completion26 November 2026
Sites1 location across South Korea

Conditions studied

Sponsor

Gangnam Severance Hospital

Who can join

Eligibility, any sex, with Severe-stage Glaucoma (Mean Deviation ≤ -20 dB). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This retrospective cohort study analyzes risk factors for central visual loss (CVL) after severe-stage glaucoma surgery. The primary hypothesis is that 1) visual prognosis is determined primarily by early postoperative intraocular pressure (IOP) stability rather than surgical choice, and 2) the nature of risk (hypotony vs hypertension) is modified by baseline visual reserve. We analyzed outcomes in 523 patients with severe-stage glaucoma who underwent trabeculectomy or Ahmed glaucoma valve (AGV) implantation, focusing on the dichotomous risk profile stratified by baseline visual acuity.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other Gangnam Severance Hospital trials

Trials by the same sponsor.

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Data sources for this page

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