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NCT07229222
A Two-Layered Simple Interrupted Myometrial Suturing Reduces Uterine Niche Formation After Primary Cesarean Section
NA trial testing Primary Cesarean Section with two-layered simple interrupted suturing of the myometrium in Cesarean Section Complications in 380 participants. Completed in 30 December 2025.
15 June 2025
Quick facts
| Lead sponsor | Benha University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 380 |
| Start date | 13 February 2025 |
| Primary completion | 15 June 2025 |
| Estimated completion | 30 December 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Primary Cesarean Section with two-layered simple interrupted suturing of the myometrium
- Primary Cesarean Section with double-layered continuous suturing of the myometrium
- Saline-infusion Sonohysterography
Conditions studied
- Cesarean Section Complications — all drugs for Cesarean Section Complications →
- Scar Niche — all drugs for Scar Niche →
- Myometrial Remodeling — all drugs for Myometrial Remodeling →
- Suture Techniques — all drugs for Suture Techniques →
Sponsor
Benha University
Who can join
Adults 18 to 45, female only, with Cesarean Section Complications or Scar Niche. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to determine whether two-layered simple interrupted myometrial suturing is superior to double-layered continuous suturing for the prevention of uterine niche formation after primary cesarean section.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07229222
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Benha University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07229222 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Benha University
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07229222.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing