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NCT07204509
Chromosomal Abnormalities in Patients With Congenital Heart Disease at Assiut University Children's Hospital
trial testing Conventional Karyotyping in Congenital Heart Disease (CHD) in 138 participants. Not yet recruiting.
1 October 2026
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 138 |
| Start date | 1 October 2025 |
| Primary completion | 1 October 2026 |
| Estimated completion | 1 December 2026 |
Drugs / interventions tested
- Conventional Karyotyping
Conditions studied
- Congenital Heart Disease (CHD) — all drugs for Congenital Heart Disease (CHD) →
- Chromosomal Abnormalities — all drugs for Chromosomal Abnormalities →
Sponsor
Assiut University
Who can join
Adults 1 Month to 18, any sex, with Congenital Heart Disease (CHD) or Chromosomal Abnormalities. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Congenital heart disease (CHD) is one of the most common birth defects and an important cause of infant morbidity and mortality. Many children with CHD also have underlying genetic abnormalities, particularly chromosomal abnormalities, which may affect their prognosis, management, and counseling. This study aims to determine the incidence and pattern of chromosomal abnormalities among children with CHD attending Assiut University Children's Hospital and Elmabara Insurance Hospital. Children with a confirmed diagnosis of CHD will undergo a detailed clinical assessment, including dysmorphic evaluation, followed by chromosomal analysis (karyotyping). The study will help identify the frequency and type of chromosomal abnormalities associated with CHD and their correlation with specific cardiac defects and phenotypic features. Understanding these genetic associations may improve diagnosis, early intervention, and family counseling, and provide useful information for risk stratification and prevention strategies in the Egyptian population.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07204509
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07204509 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 2 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07204509.
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