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NCT07196618: DMSO
Effect of Dimethyl Sulfoxide Pretreatment on Tensile Bond Strength and Nanoleakage of Resin Composite Bonded to Aged Dentin
NA trial testing dimethyl sulfoxide in Bonding in 30 participants. Participants enrolled and being followed up; not accepting new ones.
1 February 2026
Quick facts
| Lead sponsor | Al-Azhar University |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 30 |
| Start date | 1 September 2025 |
| Primary completion | 1 February 2026 |
| Estimated completion | 1 March 2026 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- dimethyl sulfoxide (DIMETHYL SULFOXIDE) — full drug profile →
- Cholorhexidine — full drug profile →
Conditions studied
- Bonding — all drugs for Bonding →
Sponsor
Al-Azhar University
Who can join
Adults 50 to 75, any sex, with Bonding. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
clinical assessment evaluation using the FDI world dental federation criteria
Time frame: post operative 2 weeks
Sponsor's own description
This study was evaluated the effect of dimethyl sulfoxide pretreatment on tensile bond strength and nanoleakage of resin composite bonded to aged dentin.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07196618
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of dimethyl sulfoxide
Trials testing the same drug.
- NCT05560919 — Acceleration of Orthodontic Tooth Movement · Phase 2, PHASE3 · completed
- NCT00118313 — Vaccine Therapy With or Without Imiquimod in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or St · Phase 1 · completed
Other recruiting trials for Bonding
Currently open trials in the same condition.
- NCT07276126 — The Effect of the Cesarean ERAS Protocol on Mother-Infant and Father-Infant Bonding: a Multicenter, Randomized Controlle · NA · recruiting
- NCT07246356 — Feasibility and Efficacy of GTEP for Birth Trauma · NA · recruiting
- NCT05709392 — Preterm DElayed Cord Clamping and Early Skin-to-Skin Contact: PreDECESS · NA · recruiting
Other Al-Azhar University trials
Trials by the same sponsor.
- NCT06489327 — Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery · NA · recruiting
- NCT07327918 — Effect of Epidural Needle Injection on Catheter Placement Success During Painless Labour · Phase 3 · not yet recruiting
- NCT07500194 — Quad Helix vs RME for Posterior Cross-bite in Egyptian Children · NA · not yet recruiting
- NCT07360756 — Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery · not yet recruiting
- NCT07343570 — Comparison of Quadratus Lumborum and Combined Groin Nerve Blocks for Postoperative Analgesia After Open Inguinal Hernia · Phase 3 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07196618 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Al-Azhar University
- Last refreshed: 10 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07196618.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing