NCT07189923

Comparative Real-world Study on Ablative Fractional CO₂ Laser vs PRP With Microneedling for Acne Scar Treatment.

Not yet recruiting NA Last updated 3 December 2025

What this trial tests

NA trial testing Ablative Fractional CO₂ Laser in Acne Scars in 116 participants. Not yet recruiting.

Timeline

1 December 2025

Primary endpoint
30 September 2026

30 November 2026

Quick facts

Lead sponsor	Dr. Sirajul Islam Medical College
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	116
Start date	1 December 2025
Primary completion	30 September 2026
Estimated completion	30 November 2026
Sites	1 location across Bangladesh

Drugs / interventions tested

• Ablative Fractional CO₂ Laser
• Platelet-Rich Plasma (PRP) With Microneedling

Conditions studied

• Acne Scars — all drugs for Acne Scars →
• Ablative Fractional CO₂ Laser Therapy — all drugs for Ablative Fractional CO₂ Laser Therapy →
• Platelet-rich Plasma (PRP) — all drugs for Platelet-rich Plasma (PRP) →

Sponsor

Dr. Sirajul Islam Medical College

Who can join

18 and older, any sex, with Acne Scars or Ablative Fractional CO₂ Laser Therapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Road traffic accidents (RTAs) remain a major public health concern worldwide and in Bangladesh, contributing significantly to injury, disability, and premature death. In resource limited settings like Bangladesh, it is crucial to understand the factors that influence survival following an RTA in order to develop effective prevention strategies and improve patient outcomes. Therefore, this study aims to determine the 30 day survival rate and identify predictors of survival among adult RTA victims treated at a tertiary care hospital in Bangladesh. The observational study will be carried out at Emergency and casualty department of Dhaka Medical College Hospital (DMCH) between October 2025 and March 2026. A total of 204 adults (≥18 years) presenting to the hospital's Casualty Department with RTA related injuries will be included. Informed written consent will be obtained from each patient or their legal guardian prior to enrollment. Data will be collected through structured face to face interviews, review of hospital records, and follow up on the 30th day of accident. The follow-up will be conducted either in person or by telephone. Variables will include patient demographics, accident circumstances, admission characteristics, injury pattern and severity, pre-hospital care, clinical condition at admission, hospital management provided, and treatment outcome. All data will be analyzed using SPSS version 25.0. Kaplan-Meier analysis will estimate survival probabilities, while Cox proportional hazards regression will be used to identify independent predictors of mortality. The findings of this study are expected to generate context-specific, evidence-based insights for strengthening trauma care protocols, gap related to emergency handling of the RTA patients, enhancing pre-hospital emergency services, and informing policy decisions aimed at reducing preventable RTA-related mortality and morbidity in Bangladesh.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.