Last reviewed · How we verify
NCT07183163: ROPIPH
The Role of Obesity in Peri-Implant Health(ROPIPH)
trial testing Clinical and biochemical assessment in Obesity &Amp; Overweight in 80 participants. Completed in 29 October 2024.
27 May 2024
Quick facts
| Lead sponsor | Mine Keskin |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 12 February 2023 |
| Primary completion | 27 May 2024 |
| Estimated completion | 29 October 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Clinical and biochemical assessment
Conditions studied
- Obesity &Amp; Overweight — all drugs for Obesity &Amp; Overweight →
- Peri Implantitis — all drugs for Peri Implantitis →
- Dental Implant — all drugs for Dental Implant →
Sponsor
Mine Keskin
Who can join
Adults 18 to 65, any sex, with Obesity &Amp; Overweight or Peri Implantitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical study aims to evaluate the influence of obesity on peri-implant health. Both clinical parameters and biochemical markers in peri-implant crevicular fluid(PICF) will be assessed. The study will include patients with dental implants who are classified as obese as well as a control group of non-obese participants. Clinical outcomes such as probing depth, plaque index, bleeding on probing, and peri-implant bone levels will be recorded. In addition, PICF samples will be analyzed for inflammatory biomarkers including interleukin-1 beta(IL-1beta), tumor necrosis factor-alpha(TNF-alfa), and matrix metalloproteinase-8(MMP-8). The results of this study may help to clarify the relationship between obesity and inflammatory responses in peri-implant tissues.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Influence of Obesity on Peri-Implant Health: A Cross-Sectional Clinical and Biochemical Study.
Keskin M, Zihni Korkmaz M, Bostan SA, Atak M. · · 2026 · PMID 41975678 · DOI 10.3390/diagnostics16070965
Verify or expand the search:
- PubMed search for NCT07183163
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Obesity &Amp; Overweight
Currently open trials in the same condition.
- NCT07231484 — Effects of Grape Consumption on the Immune-Gut Axis in Obesity · NA · recruiting
- NCT07218588 — Sanctuary Farm Prescription in Adolescents · NA · recruiting
- NCT07245771 — Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of R · Phase 1, PHASE2 · recruiting
- NCT07240246 — Effect of a Dietary Supplement on Hormones Involved in Appetite Regulation in Overweight and Obese Adults · NA · active not recruiting
- NCT07114289 — Spontaneous Breathing Trials Using Pressure Support or T-Piece in Overweight and Obese Patients · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07183163 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mine Keskin
- Last refreshed: 19 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07183163.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing