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NCT07179705: HyPIR-ICU
Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients
NA trial testing Hypotensive prediction index in Intradialytic Hypotension in 46 participants. Currently enrolling.
31 January 2026
Quick facts
| Lead sponsor | Chulalongkorn University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 46 |
| Start date | 10 October 2025 |
| Primary completion | 31 January 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Hypotensive prediction index
- Standard of care monitoring
Conditions studied
- Intradialytic Hypotension — all drugs for Intradialytic Hypotension →
- Intensive Care Unit ICU — all drugs for Intensive Care Unit ICU →
- Hemodialysis Patients — all drugs for Hemodialysis Patients →
Sponsor
Chulalongkorn University
Who can join
18 and older, any sex, with Intradialytic Hypotension or Intensive Care Unit ICU. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This single-center, crossover randomized controlled trial (HyPIR-ICU) investigates whether a Hypotension Prediction Index (HPI)-guided management strategy can reduce intradialytic hypotension (IDH) during prolonged intermittent renal replacement therapy (PIRRT) in critically ill patients. All participants must have an indwelling arterial catheter for continuous hemodynamic monitoring.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07179705
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Intradialytic Hypotension
Currently open trials in the same condition.
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- NCT07022847 — Pleth Variability Index for Predicting Low Blood Pressure During Maintenance Hemodialysis · recruiting
- NCT07033273 — Inferior Vena Cava Collapsibility Index and Intradialytic Hypotension · recruiting
- NCT05834777 — Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor · Phase 3 · recruiting
- NCT05814146 — Trial of Variable Dialysate Bicarbonate · NA · recruiting
Other Chulalongkorn University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07179705 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chulalongkorn University
- Last refreshed: 17 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07179705.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing