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NCT07178665
Pilot Trial of Preop Partial Radiation in Breast Cancer Patients
Phase 1 trial testing Radiation: Accelerated Partial Breast Irradiation (APBI) in Early-stage Breast Cancer in 98 participants. Suspended.
1 June 2027
Quick facts
| Lead sponsor | Rutgers, The State University of New Jersey |
|---|---|
| Phase | Phase 1 |
| Status | Suspended |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 98 |
| Start date | 2 September 2025 |
| Primary completion | 1 June 2027 |
| Estimated completion | 1 June 2028 |
| Sites | 10 locations across United States |
Drugs / interventions tested
- Radiation: Accelerated Partial Breast Irradiation (APBI)
Conditions studied
- Early-stage Breast Cancer — all drugs for Early-stage Breast Cancer →
- Breast Carcinoma — all drugs for Breast Carcinoma →
- DCIS — all drugs for DCIS →
Sponsor
Rutgers, The State University of New Jersey
Who can join
Adults 50 to 90, female only, with Early-stage Breast Cancer or Breast Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of our study is to assess the feasibility of preoperative partial breast (APBI) radiation in breast cancer patients. The primary outcome is the acute wound complication rate. We also aim to evaluate cosmetic outcomes and late toxicities as secondary objectives. Another goal is to examine the histopathology of tumors before and after radiation to assess the response and other immunologic and/or molecular changes to the tumor and its environment elicited by the radiation treatment. We hope that this will guide future trials that could change practice in specific patient subgroups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07178665
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Rutgers, The State University of New Jersey trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07178665 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rutgers, The State University of New Jersey
- Last refreshed: 14 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07178665.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing