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Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients

NCT07175623 NA COMPLETED

This randomized controlled trial aims to compare the interaction of methylprednisolone and dexamethasone with sugammadex in pediatric patients undergoing adenoidectomy and/or tonsillectomy. The primary objective is to evaluate the effect of these corticosteroids on the reversal time of rocuronium-induced neuromuscular block by sugammadex. Secondary outcomes include postoperative pain, nausea and vomiting, extubation time, and adverse events. Eligible participants are children aged 5 to 12 years, ASA I-II, scheduled for elective surgery under general anesthesia. The study is designed as a triple-blind, parallel-group trial with three arms: methylprednisolone, dexamethasone, and placebo.

Details

Lead sponsorKonya City Hospital
PhaseNA
StatusCOMPLETED
Enrolment60
Start dateTue Sep 16 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionSat Dec 20 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

Turkey (Türkiye)