NCT07174011 (AA) is a Phase 4 clinical trial of Roflumilast in Alopecia, sponsored by Cairo University.

Who is sponsoring NCT07174011?

NCT07174011 is sponsored by Cairo University.

What drugs are being tested in NCT07174011?

Interventions in NCT07174011: Roflumilast, intralesional steroid.

What condition does NCT07174011 study?

NCT07174011 studies Alopecia, Alopecia Areata.

Is NCT07174011 still recruiting?

NCT07174011 is currently completed. Last updated 15 September 2025.

Last reviewed 2025-09-15 · How we verify

NCT07174011: AA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Efficacy and Safety of Oral Roflumilast Versus Intralesional Corticosteroids Injection (ILCs) in the Treatment of Alopecia Areata

Completed Phase 4 Last updated 15 September 2025

What this trial tests

Phase 4 trial testing Roflumilast in Alopecia in 50 participants. Completed in 20 August 2025.

Timeline

12 January 2025

Primary endpoint
20 May 2025

20 August 2025

Quick facts

Lead sponsor	Cairo University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	50
Start date	12 January 2025
Primary completion	20 May 2025
Estimated completion	20 August 2025
Sites	1 location across Egypt

Drugs / interventions tested

Roflumilast (ROFLUMILAST) — full drug profile →
intralesional steroid

Conditions studied

Alopecia — all drugs for Alopecia →
Alopecia Areata — all drugs for Alopecia Areata →

Sponsor

Cairo University

Who can join

18 Weeks and older, any sex, with Alopecia or Alopecia Areata. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Evaluation of the Efficacy and Safety of a drug called Oral Roflumilast versus Intralesional Corticosteroids Injection (ILCs) in the Treatment of Alopecia Areata.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Roflumilast

Trials testing the same drug.

NCT07352566 — Utilization of a Microdevice for Psoriasis and Atopic Dermatitis · Phase 4 · not yet recruiting
NCT06977711 — Loncastuximab and Roflumilast Added to R-CHOP (Lo-(Rituximab and Roflumilast) RR-CHOP) for Naïve High-Risk Diffuse Large · Phase 1 · recruiting
NCT06860958 — Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients · Phase 3 · recruiting
NCT06440473 — Visualization of Topical Zoryve vs. Vehicle Using Line Field Optical Coherence Tomography in Healthy Skin · Phase 4 · recruiting
NCT05684744 — Roflumilast Versus Methotrexate in Psoriasis · Phase 2, PHASE3 · completed

Other recruiting trials for Alopecia

Currently open trials in the same condition.

NCT07422376 — Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variation · NA · recruiting
NCT07107841 — Autologous Hair Follicle Secretome for Androgenic Alopecia (Single Site) · NA · recruiting
NCT06998680 — 6-Month Trial of Chinese Herbal Treatments for Hair Loss and Gray Hair · NA · recruiting
NCT05484973 — Study to Assess the Ability of the Portable Scalp Cooling System (PSCS) to Prevent Hair Loss · NA · recruiting
NCT06215469 — Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads) · NA · recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07174011 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 15 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07174011.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing