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NCT07162649
Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in Adults
NA trial testing Dexmedetomidine in Dexmedetomidine in 400 participants. Not yet recruiting.
30 August 2027
Quick facts
| Lead sponsor | Yuan Shen |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 400 |
| Start date | 1 September 2025 |
| Primary completion | 30 August 2027 |
| Estimated completion | 30 August 2028 |
Drugs / interventions tested
- Dexmedetomidine (dexmedetomidine) — full drug profile →
- Placebo
Conditions studied
- Dexmedetomidine — all drugs for Dexmedetomidine →
Sponsor
Yuan Shen — full company profile →
Who can join
Adults 18 to 65, any sex, with Dexmedetomidine. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Panic attacks affect 13.2% of adults globally, with acute treatments (e.g., benzodiazepines) carrying dependency risks. Dexmedetomidine, an α₂-adrenergic agonist, achieves peak plasma levels in 5-15 min via nasal delivery and may offer rapid, non-invasive relief for acute panic attacks. Despite preclinical evidence of anxiolytic effects, no randomized trials have evaluated its efficacy for panic attacks.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07162649
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dexmedetomidine
Trials testing the same drug.
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- NCT07377981 — An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyp · Phase 4 · not yet recruiting
- NCT07306702 — Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients · Phase 4 · withdrawn
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
Other recruiting trials for Dexmedetomidine
Currently open trials in the same condition.
- NCT07508202 — Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Bloc · Phase 4 · recruiting
- NCT07523438 — Effect of Intranasal Dexmedetomidine on the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery · NA · recruiting
- NCT07343843 — Virtual Reality Versus Intravenous Dexmedetomidine on Maternal Anxiety, Stress, Hemodynamics, and Neonatal Outcomes Duri · NA · recruiting
- NCT07327905 — Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy · NA · recruiting
- NCT07276867 — Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia f · NA · recruiting
Other Yuan Shen trials
Trials by the same sponsor.
- NCT07196592 — Development of a Novel Multidimensional Therapeutic Intervention Protocol for MCI · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07162649 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yuan Shen
- Last refreshed: 9 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07162649.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing