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NCT07161323: CASE-SNAG
SNAG and SNME in Non-Specific Sciatic Pain
NA trial testing Sustained Natural Apophyseal Glide (SNAG) in Sciatica Pain in 30 participants. Currently enrolling.
1 July 2026
Quick facts
| Lead sponsor | Istinye University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 July 2025 |
| Primary completion | 1 July 2026 |
| Estimated completion | 1 July 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Sustained Natural Apophyseal Glide (SNAG)
- Sciatic Nerve Mobilization Exercises (SNME)
Conditions studied
- Sciatica Pain — all drugs for Sciatica Pain →
- Sciatica Acute — all drugs for Sciatica Acute →
- Mulligan Mobilization — all drugs for Mulligan Mobilization →
Sponsor
Istinye University
Who can join
Adults 20 to 50, any sex, with Sciatica Pain or Sciatica Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is designed as a crossover trial. All participants who meet the inclusion criteria and voluntarily agree to participate will be evaluated using the assessment methods detailed below. Subsequently, participants will be randomly assigned into two groups. The first group (Mulligan Concept Group - MCG) will receive the SNAG technique, while the second group (Neural Mobilization Group - NMG) will perform the Sciatic Nerve Mobilization Exercise (SNME). After the intervention, participants will be evaluated a second time. Ten days after this session, participants will be invited back. Those who were in the MCG group during the first session will be re-evaluated and then receive the SNGE intervention. Participants who were in the SNGE group during the first session will be re-evaluated and then receive the SNAG intervention. Following this second intervention, participants will be evaluated once again. Assessments will be done are Demographic Form, Visual Analogue Scale, Oswestry Disability Index, Joint Range of Motion, Five-times Sit-to-stand Test, Sit and Reach Test
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07161323
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sciatica Pain
Currently open trials in the same condition.
- NCT06696898 — Effects of SSMC With and Without Myofascial Release in Patients With Sciatica · NA · recruiting
Other Istinye University trials
Trials by the same sponsor.
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- NCT07528807 — Exercise, Pain Beliefs, and Activity Patterns in Musculoskeletal Pain · not yet recruiting
- NCT07520981 — Functional Capacity, Subjective Dyspnea and Fatigue in Smokers · not yet recruiting
- NCT07518095 — Serum Bicarbonate and Enteral Feeding Intolerance in Adult ICU: A Prospective Clinical Trial · not yet recruiting
- NCT07483190 — Effectiveness of Thoracoabdominal Nerve Block (M-TAPA) on Postoperative Pain Relief in Laparoscopic Hysterectomy · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07161323 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istinye University
- Last refreshed: 8 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07161323.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing