NCT07158073 is a NA clinical trial of FiO₂ titration, under the guidance of ORI in Rhinoplasty, sponsored by Dr. Lutfi Kirdar Kartal Training and Research Hospital.

Who is sponsoring NCT07158073?

NCT07158073 is sponsored by Dr. Lutfi Kirdar Kartal Training and Research Hospital.

What drugs are being tested in NCT07158073?

Interventions in NCT07158073: FiO₂ titration, under the guidance of ORI, Conventional oxygen administration.

What condition does NCT07158073 study?

NCT07158073 studies Rhinoplasty, Oxidative Stress, Hyperoxia, Oxygen Reserve Index.

Is NCT07158073 still recruiting?

NCT07158073 is currently completed. Last updated 8 September 2025.

Last reviewed 2025-09-08 · How we verify

NCT07158073

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of ORI-guided Oxygen Titration on Oxidative Stress in Rhinoplasty Surgery

Completed NA Last updated 8 September 2025

What this trial tests

NA trial testing FiO₂ titration, under the guidance of ORI in Rhinoplasty in 60 participants. Completed in 30 August 2021.

Timeline

1 March 2021

Primary endpoint
20 August 2021

30 August 2021

Quick facts

Lead sponsor	Dr. Lutfi Kirdar Kartal Training and Research Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	60
Start date	1 March 2021
Primary completion	20 August 2021
Estimated completion	30 August 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

FiO₂ titration, under the guidance of ORI
Conventional oxygen administration

Conditions studied

Rhinoplasty — all drugs for Rhinoplasty →
Oxidative Stress — all drugs for Oxidative Stress →
Hyperoxia — all drugs for Hyperoxia →
Oxygen Reserve Index — all drugs for Oxygen Reserve Index →

Sponsor

Dr. Lutfi Kirdar Kartal Training and Research Hospital

Who can join

18 and older, any sex, with Rhinoplasty or Oxidative Stress. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to evaluate whether the use of Oxygen Reserve Index (ORİ) can prevent hyperoxia in patients undergoing rhinoplasty surgery and whether it can reduce oxidative stress caused by hyperoxia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The effect of oxygen reserve index guided oxygen titration on oxidative stress in rhinoplasty surgery: a randomized controlled trial.
Karakaşoğlu R, Geyik FD, Çevik BE, Saraçoğlu KT. · · 2025 · PMID 41188744 · DOI 10.1186/s12871-025-03424-0

Verify or expand the search:

Other recruiting trials for Rhinoplasty

Currently open trials in the same condition.

NCT07033039 — Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre · NA · recruiting
NCT07233538 — Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty · NA · recruiting
NCT06966518 — Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Open Rhinoplasty · NA · recruiting
NCT06510881 — Single Stage Versus Multiple Staged Repair of Nasal & Alveolar Deformities in Patients With Cleft Lip and Palate · NA · recruiting
NCT03925389 — Outcome Analysis in Septorhinoplasty · recruiting

Other Dr. Lutfi Kirdar Kartal Training and Research Hospital trials

Trials by the same sponsor.

NCT07322497 — Comparison of Video Based Phone App vs. Supervised Preoperative Exercise for ACL Reconstruction · NA · not yet recruiting
NCT07141966 — Assessment of Physical Activity, Balance, Muscle Strength, and Cognitive Function in Patients Diagnosed With Schizophren · completed
NCT07142018 — Investigation of the Effect of Hyperbaric Oxygen Therapy in Patients With Avascular Necrosis · active not recruiting
NCT07144553 — Relationship Between Eating Disorders, Anthropometric Characteristics, and Physical Activity After Bariatric Surgery · completed
NCT07140042 — Physical Fitness, Physical Activity Level, Depression and Quality of Life in Bipolar and Schizophrenia Patients · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07158073 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Dr. Lutfi Kirdar Kartal Training and Research Hospital
Last refreshed: 8 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07158073.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing