NCT07156786 is a Phase 2, PHASE3 clinical trial of N-acetylcysteine (NAC) in Kidney Function Issue, sponsored by Fakultas Kedokteran Universitas Indonesia.

Who is sponsoring NCT07156786?

NCT07156786 is sponsored by Fakultas Kedokteran Universitas Indonesia.

What drugs are being tested in NCT07156786?

Interventions in NCT07156786: N-acetylcysteine (NAC), Placebo.

What condition does NCT07156786 study?

NCT07156786 studies Kidney Function Issue, Acute Kidney Injury, Cancer (Solid Tumors), Kidney Function Tests, Acetylcysteine Adverse Reaction.

Is NCT07156786 still recruiting?

NCT07156786 is currently not yet recruiting. Last updated 19 September 2025.

Last reviewed 2025-09-19 · How we verify

NCT07156786

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

N-Acetylcysteine Roles in Preserving Renal Function Measured by Urinary KIM-1 (Kidney Injury Molecule-1) and Serum Creatinine on Cancer Patients With Cisplatin Based Chemotherapy: A Randomized Placebo-Controlled Trial

Not yet recruiting Phase 2, PHASE3 Last updated 19 September 2025

What this trial tests

Phase 2, PHASE3 trial testing N-acetylcysteine (NAC) in Kidney Function Issue in 72 participants. Not yet recruiting.

Timeline

15 September 2025

Primary endpoint
30 April 2027

31 August 2027

Quick facts

Lead sponsor	Fakultas Kedokteran Universitas Indonesia
Phase	Phase 2, PHASE3
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	72
Start date	15 September 2025
Primary completion	30 April 2027
Estimated completion	31 August 2027

Drugs / interventions tested

N-acetylcysteine (NAC)
Placebo

Conditions studied

Kidney Function Issue — all drugs for Kidney Function Issue →
Acute Kidney Injury — all drugs for Acute Kidney Injury →
Cancer (Solid Tumors) — all drugs for Cancer (Solid Tumors) →
Kidney Function Tests — all drugs for Kidney Function Tests →

Sponsor

Fakultas Kedokteran Universitas Indonesia — full company profile →

Who can join

18 and older, any sex, with Kidney Function Issue or Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to learn if N-Acetylcysteine drug works to protect kidney function in adults patient with cancer. Kidney function will be measured by laboratory parameter using urine sample (KIM-1 urine) and blood sample (serum creatinine). The main questions it aims to answer are: 1. Does N-Acetylcysteine lower the level of KIM-1 (Kidney Injury Molecule) in patients urine indicating kidney function protection? 2. Does N-Acetylcysteine lower the level of creatinine in patients blood indicating kidney function protection? Participants will: 1. Had their blood and urine sample taken before taking the drugs (N-Acetylcysteine or placebo) 2. Underwent cisplatin based chemotherapy 3. Taken placebo or N-Acetylcysteine for seven days (1 day before chemotherapy, on the chemotherapy day, and 5 days after chemotherapy) 4. Had their blood and urine sample taken twice after taking the drugs (1 week and 3 weeks after chemotherapy) 5. Had their symptoms monitor during and after taking the drugs. Every possible side effect, hospitalization, or death will be recorded.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of N-acetylcysteine (NAC)

Trials testing the same drug.

NCT04928495 — Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 · Phase 3 · unknown
NCT04013555 — The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia · Phase 1, PHASE2 · completed
NCT03881163 — A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Single and Multiple Intravenous Doses of N-acetylcystei · Phase 1 · completed
NCT03636932 — RENACTIF: Reduction of the Thrombotic Phenotype in Renal Insufficiency With N-AcetylCysteine · Phase 2 · completed
NCT04481035 — Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1 · Phase 2 · completed

Other recruiting trials for Kidney Function Issue

Currently open trials in the same condition.

NCT06219798 — Evaluation of a Pathway on the Evolution of Renal Function in Patients With Advanced Chronic Kidney Disease · recruiting

Other Fakultas Kedokteran Universitas Indonesia trials

Trials by the same sponsor.

NCT07308275 — Longitudinal Evaluation of Direct Neurotization Technique in Breast Reconstruction With Fully Autologous Components · NA · not yet recruiting
NCT06521957 — Effectiveness of CBT in Improving Psycho-Neuro-Endocrine Factors in Women Following In Vitro Fertilization Program · NA · recruiting
NCT05451433 — The Effect of Saccharomyces Boulardii in Clinical Presentation and Quality of Life Patient With IBS · NA · unknown
NCT05215301 — Assessment of Multidimensional Voice Program (MDVP) Parameters in Workers · unknown
NCT05005637 — The Effectivity of Anti Tuberculosis Therapy in Idiopathic Uveitis with Positive IGRA · Phase 2 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07156786 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Fakultas Kedokteran Universitas Indonesia
Last refreshed: 19 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07156786.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing