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NCT07156006: BAKER
Breast Arterial Calcifications as an Imaging Biomarker of Cardiovascular Risk
trial testing Mammography in Breast in 149 participants. Terminated before completion.
29 April 2024
Quick facts
| Lead sponsor | IRCCS Policlinico S. Donato |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 149 |
| Start date | 11 September 2020 |
| Primary completion | 29 April 2024 |
| Estimated completion | 29 April 2024 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Mammography
Conditions studied
- Breast — all drugs for Breast →
- Cardiovascular Calcification — all drugs for Cardiovascular Calcification →
Sponsor
IRCCS Policlinico S. Donato
Who can join
40 and older, female only, with Breast or Cardiovascular Calcification. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to assess if there is an association between the presence of BAC and traditional cardiovascular risk factors and validate a Convolutional Neural Network (CNN) for the automatic segmentation of Breast Arterial Calcifications (BAC) in mammographic images. This study focuses on understanding the potential of BAC as an imaging biomarker for cardiovascular risk. The main questions it aims to answer are: * Is there an association between the presence of BAC and traditional cardiovascular risk factors? * Can a CNN accurately segment BAC in mammographic images? * What is the correlation between BAC and White Matter Hyperintensities (WMH) detected through brain MRI? Participants in this study will be individuals who undergo mammographic screening. The main tasks participants will be asked to do include providing consent for participation and having mammographic images and a blood sample taken. The study will use a comparison group, comparing individuals with BAC to those without BAC, to assess potential effects on cardiovascular risk.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07156006
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07156006 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS Policlinico S. Donato
- Last refreshed: 4 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07156006.
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