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NCT07154524: IFTOC

Immunoadsorption for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Recruiting now Last updated 11 September 2025
What this trial tests

trial in Chronic Inflammatory Demyelinating Polyneuropathy in 140 participants. Currently enrolling.

Timeline
27 August 2025
Primary endpoint
27 February 2029
27 August 2029

Quick facts

Lead sponsorUniversity of Ulm
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment140
Start date27 August 2025
Primary completion27 February 2029
Estimated completion27 August 2029
Sites1 location across Germany

Conditions studied

Sponsor

University of Ulm

Who can join

18 and older, any sex, with Chronic Inflammatory Demyelinating Polyneuropathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is designed as an explorative study aiming at exploring safety and efficacy of immunoadsorption (IA) in patients with Chronic Inflammatory Demyelinating Poly-neuropathy (CIDP) compared to intravenous immunoglobulins (IVIg) and methyl-prednisolone (MP). For this purpose, approximately 140 patients with CIDP will be included within the framework of the German multicenter network "Kompetenznetz Peripherer Nerv" (KKPNS). The study will be purely observational. IA will be performed as an escalation therapy, i.e., in patients who did not respond to IVIg and/or MP treatment. Patients will be included in the study during ongoing IVIg or MP treatment and switched to IA during the 18-month observation period in case of an insufficient response. IA will be performed according to the therapeutic scheme of each participating center. A non-mandatory recommendation for number of sessions, treatment volumes, and frequency will be given (see below). Six-month follow-up visits including collection of standardized clini-cal data will be performed.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Chronic Inflammatory Demyelinating Polyneuropathy

Currently open trials in the same condition.

Other University of Ulm trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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