Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients (CESAR)

NCT07153406 PHASE3 NOT_YET_RECRUITING

Phase III, open label, randomised, multicentre, blind for evaluators clinical trial to evaluate the efficacy of esketamine nasal spray at flexible dosis compared to aripiprazole in elderly participants (\>60 years) who suffer from treatment-resistant major depressive

Details

Lead sponsor	Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Phase	PHASE3
Status	NOT_YET_RECRUITING
Enrolment	220
Start date	Mon Sep 15 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Jan 15 2029 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Depressive Disorder

Interventions

• Experimental regimen
• Control regimen

Countries

Spain