NCT07142395

Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay

Completed NA Last updated 5 September 2025

What this trial tests

NA trial testing Immediate skin closure in Laparotomy Closure After Abdominal Surgery in 82 participants. Completed in 15 August 2025.

Timeline

16 May 2025

Primary endpoint
15 August 2025

15 August 2025

Quick facts

Lead sponsor	Bkahtawar Amin Medical and Dental College Multan
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	82
Start date	16 May 2025
Primary completion	15 August 2025
Estimated completion	15 August 2025
Sites	1 location across Pakistan

Drugs / interventions tested

• Immediate skin closure
• Delayed primary closure

Conditions studied

• Laparotomy Closure After Abdominal Surgery — all drugs for Laparotomy Closure After Abdominal Surgery →

Sponsor

Bkahtawar Amin Medical and Dental College Multan

Who can join

Adults 18 to 60, any sex, with Laparotomy Closure After Abdominal Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or waiting a few days before closing the skin (called delayed primary closure).

Wound infection is a common problem after emergency abdominal surgery (also called laparotomy). Some surgeons close the skin right away, while others wait a few days to reduce the risk of infection.

This study will help find out which method is better.

The main questions the study aims to answer are:

1. . Does delayed primary closure lower the rate of wound infection compared to primary closure?
2. . Does the wound open up (wound dehiscence) less often with delayed closure?
3. . Does delayed closure affect the length of hospital stay?

In this clinical trial:

* Adult patients needing emergency abdominal surgery will be included.
* Half the patients will have their wounds closed immediately (primary closure), and half will have delayed closure after 3-5 days of daily dressing.
* All surgeries will be done by experienced surgeons using the same technique.
* Patients will be followed for 4 weeks after surgery to monitor wound infection, wound opening, and length of hospital stay.

The results will help doctors choose the safest and most effective way to close surgical wounds after emergency abdominal surgery.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.