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NCT07140289
Effect of Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) on Gastric Emptying
trial testing Ultrasound of gastric contents in Gastric Emptying in 100 participants. Enrolling by invitation.
1 June 2027
Quick facts
| Lead sponsor | Wael Saasouh, MD |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 September 2025 |
| Primary completion | 1 June 2027 |
| Estimated completion | 1 June 2028 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Ultrasound of gastric contents
Conditions studied
- Gastric Emptying — all drugs for Gastric Emptying →
- Glucagon-Like Peptide-1 Receptor Agonists — all drugs for Glucagon-Like Peptide-1 Receptor Agonists →
- Intermittent Fasting — all drugs for Intermittent Fasting →
- Intraoperative Complication Due to Anesthesia — all drugs for Intraoperative Complication Due to Anesthesia →
Sponsor
Wael Saasouh, MD
Who can join
Adults 18 to 90, any sex, with Gastric Emptying or Glucagon-Like Peptide-1 Receptor Agonists. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to assess the effect of using Glucagon-like peptide-1 receptor agonists (GLP-1) receptor agonists on gastric emptying on surgical patients and whether specific guidelines need to be established for these patients. GLP-1 receptor agonists are mainly used for the treatment and mitigation of obesity and metabolic syndromes. One of their mechanisms of action is by delaying gastric emptying, hence increasing satiety. However, patients need to abstain from eating for a set amount of time before surgery to reduce the risk of aspiration. Hence patients who use GLP-1 receptor agonists may need more time to abstain eating (nil-per-os). In this study we aim to assess how much time is sufficient before surgery in these specific population of patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07140289
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Gastric Emptying
Currently open trials in the same condition.
- NCT06008509 — POCUS for Gastric Emptying in Emergency Surgery · NA · recruiting
- NCT04229043 — Gastric Emptying of Water and Sports Drink in Labor · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07140289 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wael Saasouh, MD
- Last refreshed: 3 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07140289.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing