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NCT07137156
Metagenomic Analysis of the Oral Microbiome in Patients With Oral Lichen Planus: A Pilot Study in the Turkish Population
trial testing cytobrush in Oral Lichen Planus in 13 participants. Completed in 15 June 2024.
15 March 2024
Quick facts
| Lead sponsor | Kahramanmaras Sutcu Imam University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 13 |
| Start date | 15 December 2023 |
| Primary completion | 15 March 2024 |
| Estimated completion | 15 June 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- cytobrush
- next-generation sequencing
Conditions studied
- Oral Lichen Planus — all drugs for Oral Lichen Planus →
Sponsor
Kahramanmaras Sutcu Imam University
Who can join
Adults 18 to 80, any sex, with Oral Lichen Planus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lichen planus is a common chronic mucocutaneous inflammatory disease that affects the skin, nails, eyes, urogenital system, and oral mucosa. Oral lichen planus (OLP) specifically occurs in the oral cavity. As a variant of lichen planus, OLP is believed to affect the oral mucosa through T-cell-mediated chronic inflammation, and some researchers suggest that Th2-mediated inflammation may also contribute to its pathogenesis. The absence of metagenomic analyses targeting oral microbiome profiling in OLP patients in Türkiye highlights the need for studies in this field. This pilot study, conducted for the first time in Türkiye, examined microbial diversity and dominant bacterial families in the lesional and non-lesional oral sites of Turkish individuals with OLP, compared with healthy individuals. The findings are expected to contribute to identifying potential microbial targets that may play a role in OLP pathogenesis and to shaping future treatment strategies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07137156
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Oral Lichen Planus
Currently open trials in the same condition.
- NCT06981767 — Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus · Phase 2 · recruiting
- NCT07131813 — Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus · Phase 4 · recruiting
- NCT06932848 — The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus · NA · recruiting
- NCT07100613 — Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus · Phase 2 · recruiting
- NCT06233591 — Evaluating LP-10 in Subjects With OLP · Phase 2 · active not recruiting
Other Kahramanmaras Sutcu Imam University trials
Trials by the same sponsor.
- NCT07511322 — Enteral Nutrition Education Provided Using the Pecha Kucha Method · enrolling by invitation
- NCT07515287 — Restoration of Sensorimotor Function in Middle-Aged Women With Chronic Lumbar Disc Herniation: The Effect of Pilates on · NA · enrolling by invitation
- NCT07451691 — The Effect of the World Health Organisation-Based Intrapartum Care Model on Labour Pain, Comfort, Satisfaction and Postp · NA · not yet recruiting
- NCT07471412 — Sexually Transmitted Infections in Migrant Women · NA · not yet recruiting
- NCT07332065 — The Effects of Mandala Coloring on Women During Menopause · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07137156 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kahramanmaras Sutcu Imam University
- Last refreshed: 22 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07137156.
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