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NCT07137013
Periodontitis Severity in Patients With Diabetic Retinopathy
trial in Diabetic Retinopathy in 100 participants. Completed in 23 June 2025.
12 May 2025
Quick facts
| Lead sponsor | Recep Tayyip Erdogan University Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 24 February 2025 |
| Primary completion | 12 May 2025 |
| Estimated completion | 23 June 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Diabetic Retinopathy — all drugs for Diabetic Retinopathy →
- Periodontitis — all drugs for Periodontitis →
Sponsor
Recep Tayyip Erdogan University Training and Research Hospital
Who can join
Adults 60 to 85, any sex, with Diabetic Retinopathy or Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this observational study is to investigate the relationship between periodontal disease severity and retinal layer thickness in patients diagnosed with diabetic retinopathy (DR), using optical coherence tomography (OCT) for assessment. The main question this study seeks to answer is: Do measurable changes in retinal layer thickness occur as periodontal disease severity increases in patients with diabetic retinopathy? Participants will include adult individuals with a confirmed clinical diagnosis of DR. Periodontal status will be assessed through standard clinical parameters, including plaque index, probing pocket depth, clinical attachment loss, and bleeding on probing. Retinal layer thickness will be measured using high-resolution OCT and OCT angiography (OCTA) devices. The study aims to analyze potential associations between periodontal disease severity and morphological as well as vascular changes in the retina.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The Effect of Periodontitis Severity on Diabetic Retinopathy: An Optical Coherence Tomography Study
Turkogullari H, Aydogan G, Yorgancilar N, Kose O, et al · · 2026 -
The Effect of Periodontitis Severity on Diabetic Retinopathy: An Optical Coherence Tomography Study.
Turkogullari H, Aydogan GN, Yorgancilar N, Kose O, et al · · 2026 · PMID 41827930 · DOI 10.3390/diagnostics16050654
Verify or expand the search:
- PubMed search for NCT07137013
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Recep Tayyip Erdogan University Training and Research Hospital trials
Trials by the same sponsor.
- NCT07427095 — The Relationship Between Ultra-Processed Food Consumption and Oral Health · not yet recruiting
- NCT07427069 — Chronic Kidney Disease Associated Diet · not yet recruiting
- NCT07462104 — Metabolic Syndrome Associated Diet · not yet recruiting
- NCT07354815 — Metabolic Syndrome-Associated Periodontal Inflammatory Surface Area · not yet recruiting
- NCT07287540 — Anti-inflammatory Nutrition on the Outcomes of Non-surgical Periodontal Therapy · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07137013 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Recep Tayyip Erdogan University Training and Research Hospital
- Last refreshed: 22 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07137013.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing