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NCT07131579: Dexmedetomidin
Intravenous Regional Analgesia of Dexmedetomidine
NA trial testing Normal Saline in Dexmedetomidine Analgesia in 100 participants. Enrolling by invitation.
30 December 2026
Quick facts
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 100 |
| Start date | 12 January 2026 |
| Primary completion | 30 December 2026 |
| Estimated completion | 30 August 2027 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Normal Saline
- Dexmedetomidine (dexmedetomidine) — full drug profile →
Conditions studied
- Dexmedetomidine Analgesia — all drugs for Dexmedetomidine Analgesia →
- Knee Surgery — all drugs for Knee Surgery →
Sponsor
Mansoura University
Who can join
Adults 18 to 60, any sex, with Dexmedetomidine Analgesia or Knee Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist that exerts its effects by inhibiting the release of norepinephrine at presynaptic nerve terminals, leading to reduced sympathetic activity; This mechanism results in analgesia, sedation, and anxiolysis without significant respiratory depression
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07131579
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07131579 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mansoura University
- Last refreshed: 21 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07131579.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing