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NCT07125495: Tootbrush_ICU
The Effect of an Suction Toothbrush on the Development of Ventilator-Associated Pneumonia
NA trial testing Suction tootbrush and distiled water in Infection in 90 participants. Participants enrolled and being followed up; not accepting new ones.
1 December 2025
Quick facts
| Lead sponsor | Koç University |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | screening |
| Enrollment | 90 |
| Start date | 1 February 2025 |
| Primary completion | 1 December 2025 |
| Estimated completion | 20 December 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Suction tootbrush and distiled water
- suction tootbrush and .12% chlorhexidine gluconate
- Oral care sponge and with 15 ml of 0.12% chlorhexidine gluconate oral solution
Conditions studied
- Infection — all drugs for Infection →
- Intensive Care (ICU) — all drugs for Intensive Care (ICU) →
- Intubation — all drugs for Intubation →
- Intubation Complication — all drugs for Intubation Complication →
Sponsor
Koç University
Who can join
18 and older, any sex, with Infection or Intensive Care (ICU). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Literature suggests that suction toothbrushes may improve oral care in intubated patients by facilitating secretion removal and reducing microaspiration. This could decrease the need for endotracheal suctioning and lower the risk of ventilator-associated pneumonia (VAP). Therefore, this study aimed to examine the effect of a suction toothbrush on the development of VAP in intubated patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07125495
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07125495 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Koç University
- Last refreshed: 17 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07125495.
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