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NCT07117786

Computed Tomography Radiomics-Derived Nomogram for Predicting Early Renal Function Decline After Partial Nephrectomy in Renal Cell Carcinoma: A Multicenter Development/Validation Study

Completed Last updated 12 August 2025
What this trial tests

trial testing CT Contrast in Renal Cell Carcinoma (RCC) in 1,437 participants. Completed in 1 June 2023.

Timeline
1 January 2016
Primary endpoint
6 May 2023
1 June 2023

Quick facts

Lead sponsorFirst Affiliated Hospital of Fujian Medical University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment1,437
Start date1 January 2016
Primary completion6 May 2023
Estimated completion1 June 2023

Drugs / interventions tested

Conditions studied

Sponsor

First Affiliated Hospital of Fujian Medical University

Who can join

18 and older, any sex, with Renal Cell Carcinoma (RCC). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this observational study is to explore the relationship between CT-based radiomics and postoperative renal function changes in patients with localized renal cell carcinoma (RCC) undergoing partial nephrectomy (PN). The main question it aims to answer is: Can a radiomics-clinical nomogram integrating CT-based radiomics features with preoperative and intraoperative clinical variables accurately predict early postoperative renal function decline in patients with localized RCC undergoing PN? Participants already undergoing renal CT examination and scheduled for postoperative renal function testing as part of the routine perioperative care will receive renal function assessment after completing surgical treatment for RCC.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Computed tomography radiomics-derived nomogram for prediciting early renal function decline after partial nephrectomy in renal cell carcinoma: a multicenter development/validation study.
    Chen SH, Wu XH, Zeng CL, Zhao LN, et al · · 2026 · PMID 41586593 · DOI 10.1097/js9.0000000000004782

Verify or expand the search:

Other recruiting trials for Renal Cell Carcinoma (RCC)

Currently open trials in the same condition.

Other First Affiliated Hospital of Fujian Medical University trials

Trials by the same sponsor.

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Data sources for this page

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