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NCT07114835
Low-Intensity BFR Cycling: Impact on VO₂Max and Muscle Adaptations
NA trial testing Cycling with Blood Flow Restriction (15 min at 40% VO₂max with 60-80% LOP) in Aerobic Capacity in 24 participants. Completed in 5 March 2024.
5 March 2024
Quick facts
| Lead sponsor | Kahramanmaras Sutcu Imam University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 24 |
| Start date | 1 December 2023 |
| Primary completion | 5 March 2024 |
| Estimated completion | 5 March 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Cycling with Blood Flow Restriction (15 min at 40% VO₂max with 60-80% LOP)
- Cycling Exercise (40 min at 40% VO₂max)
- Short-Duration Cycling Control (15 min at 40% VO₂max)
Conditions studied
- Aerobic Capacity — all drugs for Aerobic Capacity →
- Blood Flow Restriction (BFR) Training Effects — all drugs for Blood Flow Restriction (BFR) Training Effects →
- Blood Flow Restriction Exercise — all drugs for Blood Flow Restriction Exercise →
- Muscle Strengh — all drugs for Muscle Strengh →
Sponsor
Kahramanmaras Sutcu Imam University
Who can join
Adults 18 to 24, male only, with Aerobic Capacity or Blood Flow Restriction (BFR) Training Effects. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate the effects of low-intensity cycling exercise combined with blood flow restriction (BFR) on maximal oxygen consumption (VO₂max), muscle strength, and muscle thickness in sedentary adult males. Participants will be randomly assigned to three groups: (1) a cycling exercise group performing 40 minutes of cycling at 40% VO₂max, (2) a cycling with blood flow restriction group performing 15 minutes of cycling at 40% VO₂max with limb occlusion pressure at 60-80%, and (3) a control group following a shorter cycling protocol. Muscle thickness, isokinetic knee strength, and VO₂max will be measured before and after the 9-week intervention. The study is designed to evaluate whether short-duration, low-intensity cycling with BFR can induce physiological adaptations comparable to traditional longer-duration cycling protocols.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The effect of Low-Intensity Cycling Exercise Combined with Blood Flow Restriction on VO2max, Muscle Strength, and Muscle Thickness
YAVUZ G, AKTUĞ ZB, İBİŞ S, PİŞKİN NE, et al · · 2025 · DOI 10.21203/rs.3.rs-6888223/v1
Verify or expand the search:
- PubMed search for NCT07114835
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07114835 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kahramanmaras Sutcu Imam University
- Last refreshed: 11 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07114835.
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