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NCT07112313: FQRS-TKA
Frontal QRS Axis Changes in Patients Undergoing Total Knee Arthroplasty With Spinal Anesthesia (FQRS-TKA)
trial in Spinal Anesthesia in 80 participants. Completed in 1 October 2025.
1 October 2025
Quick facts
| Lead sponsor | Sevim Şenol Karataş |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 1 September 2025 |
| Primary completion | 1 October 2025 |
| Estimated completion | 1 October 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Spinal Anesthesia — all drugs for Spinal Anesthesia →
- Total Knee Arthroplasty — all drugs for Total Knee Arthroplasty →
Sponsor
Sevim Şenol Karataş
Who can join
Adults 45 to 85, any sex, with Spinal Anesthesia or Total Knee Arthroplasty. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective, single-center, observational study aims to evaluate changes in the frontal QRS axis on ECG before and after spinal anesthesia in patients undergoing total knee arthroplasty. The primary objective is to determine whether spinal anesthesia causes a significant alteration in the frontal QRS axis. A total of 80 patients will be enrolled, and preoperative and postoperative ECG measurements will be compared using paired t-test or Wilcoxon signed-rank test depending on data distribution.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07112313
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT07339475 — Femoral Vein Diameter to Predict Intraoperative Hypotension in Geriatric Patients Undergoing Orthopedic Surgery Under Sp · recruiting
- NCT07256548 — Machine Learning for Predicting Spinal Anesthesia Duration · recruiting
Other Sevim Şenol Karataş trials
Trials by the same sponsor.
- NCT07205224 — Inflammatory Response Under Spinal vs General Anesthesia in PCNL: NLR, RDW, LAR. · completed
- NCT07188922 — Effect of Transition From Mechanical Ventilation to Spontaneous Breathing on Intraocular Pressure in ICU (VENT-IOP) · completed
- NCT07190508 — Pre-Sedation Fluid Replacement and Duodenal Passage Effects on Intraocular Pressure · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07112313 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sevim Şenol Karataş
- Last refreshed: 3 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07112313.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing