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NCT07111325: iEVs
Safety and Preliminary Efficacy of iEVs Injection in Treating Lateral Epicondylitis of Humerus
Phase 1, PHASE2 trial testing iEV in Lateral Epicondylitis in 24 participants. Currently enrolling.
1 December 2025
Quick facts
| Lead sponsor | Shanghai 6th People's Hospital |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 1 July 2023 |
| Primary completion | 1 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
Conditions studied
- Lateral Epicondylitis — all drugs for Lateral Epicondylitis →
Sponsor
Shanghai 6th People's Hospital
Who can join
18 and older, any sex, with Lateral Epicondylitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Evaluate the safety and preliminary efficacy of human induced pluripotent stem cell-derived extracellular vesicle (iEV) injection in the treatment of lateral epicondylitis of the humerus.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Mesenchymal Stem Cell Secretome in Tendon Regeneration: Therapeutic Potential, Mechanisms of Action, and Future Perspectives.
Dias TD, Anderson DE. · · 2026 · PMID 42121916 · DOI 10.3390/cells15090815
Verify or expand the search:
- PubMed search for NCT07111325
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of iEV
Trials testing the same drug.
- NCT07145294 — Induced Pluripotent Stem Cells-derived Small Extracellular Vesicles May Promote Neurological Function and Improve Cognit · Phase 1, PHASE2 · recruiting
Other recruiting trials for Lateral Epicondylitis
Currently open trials in the same condition.
- NCT07424794 — Mobilization With Movement Verses Cyriax Techniques Among Athletes With Lateral Epicondylitis · NA · recruiting
- NCT07365033 — Eccentric Exercise With Blood Flow Restriction vs Resistance Training for Lateral Epicondylitis · NA · recruiting
- NCT07342426 — High and Low Dose High-intensity Laser Therapy Lateral Epicondylitis · Phase 4 · recruiting
- NCT07410663 — Hyaluronic Acid and Amino Acid Combination Versus Exercise for Chronic Lateral Epicondylitis · active not recruiting
- NCT07314840 — Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis · recruiting
Other Shanghai 6th People's Hospital trials
Trials by the same sponsor.
- NCT07482891 — An Exploratory Study on Efficacy and Safety of Fosaprepitant and Palonosetron Hydrochloride for Injection in Preventing · Phase 4 · not yet recruiting
- NCT07414277 — CGM for Insulin-Treated T2DM During Post-Discharge Transition · NA · not yet recruiting
- NCT07359053 — MAGNATE-S: Paclitaxel Polymer Micelles Combo in Advanced Sarcoma · Phase 2 · recruiting
- NCT07288372 — The CGM-OGTT Glycemic Homeostasis Study · not yet recruiting
- NCT06936657 — Intervention Effects of Optimized Carbohydrate Diet in Patients With Type 2 Diabetes · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07111325 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shanghai 6th People's Hospital
- Last refreshed: 8 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07111325.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing