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NCT07110311

Impact of Pet Cats on Nasal and Gut Microbiota in Patients With Cat Allergen Allergy

Recruiting now Last updated 7 August 2025
What this trial tests

trial in Allergic Rhinitis in 100 participants. Currently enrolling.

Timeline
14 November 2024
Primary endpoint
1 November 2026
1 November 2032

Quick facts

Lead sponsorThe First Affiliated Hospital with Nanjing Medical University
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment100
Start date14 November 2024
Primary completion1 November 2026
Estimated completion1 November 2032
Sites1 location across China

Conditions studied

Sponsor

The First Affiliated Hospital with Nanjing Medical University

Who can join

Adults 18 to 65, any sex, with Allergic Rhinitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It has been reported that the incidence of allergic rhinitis (AR) is as high as 24.1% in adults and 16.8% in children in China. A study explored the changes in the incidence of AR in China, and the study showed that the incidence of AR in many cities in China increased significantly from 2005 to 2011. The latest Chinese guidelines for the diagnosis and treatment of allergic rhinitis pointed out that AR is an independent risk factor for asthma, and 40% of AR patients can be complicated with asthma. CARRAD reported that in adult asthma patients who received skin prick test or serum specific IgE (sIgE) for allergens, The positive rates of at least one allergen were 65.4% and 75.4%, respectively. With the acceleration of urbanization and the improvement of people's economic level, more and more families keep pets. Pets can promote people's physical and mental health, but there are also more and more people who are allergic to pets. Some studies have shown that pets are the third major allergen of respiratory allergic diseases, next to dust mites and pollen. Cats are by far one of the most popular pets, but in recent years, the prevalence of cat allergen has gradually increased. Animal allergens are present in saliva, urine, and dander, and they spread into the environment by adhering to the hair and dander of the animals, such that even in homes without pets, the level of allergens in the environment is sufficient to sensitize people. However, at present, the microbial impact of the microorganisms carried by pet cats on their owners and the living environment is unknown.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Allergic Rhinitis

Currently open trials in the same condition.

Other The First Affiliated Hospital with Nanjing Medical University trials

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Data sources for this page

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