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NCT07108400
Efficacy of a Combination of Ultrasound-guided Intra-articular Injections of Hyaluronic Acid, High-power Laser Therapy and Rehabilitation on Functioning in Patients Affected by Hip Osteoarthritis.
NA trial testing ultrasound-guided injections of hyaluronic acid plus high-power laser therapy in Hip Osteoarthritis in 57 participants. Currently enrolling.
3 August 2025
Quick facts
| Lead sponsor | De Sire Alessandro |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 57 |
| Start date | 17 March 2022 |
| Primary completion | 3 August 2025 |
| Estimated completion | 12 December 2025 |
| Sites | 2 locations across Italy |
Drugs / interventions tested
- ultrasound-guided injections of hyaluronic acid plus high-power laser therapy
- ultrasound-guided injections of hyaluronic acid plus sham" high-power laser therapy
Conditions studied
- Hip Osteoarthritis — all drugs for Hip Osteoarthritis →
Sponsor
De Sire Alessandro
Who can join
Adults 18 to 85, any sex, with Hip Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
High-power laser therapy (HPLT) is effective in treating musculoskeletal conditions, reducing pain and improving joint functionality. This randomized controlled trial (RCT) aimed to explore the effectiveness of a combination of HPLT, hyaluronic acid injections, and rehabilitation for patients with hip osteoarthritis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Combined ultrasound-guided hyaluronic acid injections, high-power laser therapy and physiotherapy improve hip function in osteoarthritis: A randomized controlled trial.
de Sire A, Marotta N, Bartalotta I, Prestifilippo E, et al · · 2026 · PMID 42255387 · DOI 10.1002/jeo2.70685
Verify or expand the search:
- PubMed search for NCT07108400
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hip Osteoarthritis
Currently open trials in the same condition.
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- NCT07327931 — PENG Block Variants With Dexamethasone and Dexmedetomidine in Older Adults · NA · recruiting
- NCT07288983 — PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery · NA · recruiting
- NCT07327372 — PENG Block With Dexmedetomidine in Older Adults · NA · recruiting
- NCT07347041 — Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Hip Osteoarthritis(OA) · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07108400 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by De Sire Alessandro
- Last refreshed: 7 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07108400.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing