Comparison of Dexmedetomidine Versus Fentanyl or Magnesium Sulphate as Adjuncts to Propofol-Based Total Intravenous Anesthesia in Patients Undergoing Craniotomy

NCT07105618 NA RECRUITING

Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.

Details

Lead sponsor	Zagazig University
Phase	NA
Status	RECRUITING
Enrolment	108
Start date	2025-08-10
Completion	2027-04

Conditions

• Anesthesia

Interventions

• Dexmedetomidine
• Fentanyl
• Magnesium

Primary outcomes

• The total intraoperative propofol consumption — 4 hours
  The total intraoperative propofol consumption (in milligrams).

Countries

Egypt