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Autonomic Neural Blockade During Sleeve Gastrectomy and Gastric Bypass: A Randomized Controlled Trial Evaluating Pain and Nausea After Bariatric Surgery
The purpose of this research is to evaluate if autonomic nerve block (ANB- blocking pain and nausea signals) decreases pain and anti-nausea medication requirements as well as the experience of pain/nausea during the first 72 hours after sleeve gastrectomy or gastric bypass surgery. Participants will be randomly assigned either to the standard of care or the ANB group before surgery. As part of standard of care, in both groups, laparoscopic bariatric surgery will be initiated with local anesthetic injected into the abdominal wall. In the ANB group, participants will be given an additional injection of local anesthetic medication to block nerves on and around the stomach.
Details
| Lead sponsor | Endeavor Health |
|---|---|
| Phase | NA |
| Status | NOT_YET_RECRUITING |
| Enrolment | 200 |
| Start date | 2026-03 |
| Completion | 2027-12 |
Conditions
- Bariatric Surgery Candidate
- Pain, Postoperative
- Nausea and Vomiting, Postoperative
- Opioid Use
Interventions
- Intraoperative autonomic neural blockade (ANB)
- Laparoscopic Standard of Care Abdominal Wall Block
Primary outcomes
- Pain medication consumed post-operatively — Post-op 72 hours
Total Morphine milligram equivalents (MMEs) of pain medication utilized during the first 72hrs after bariatric surgery
Countries
United States