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NCT07099807
Carbohydrate Mouth Rinsing and Cognitive Response During Exercise
NA trial testing Carbohydrate Mouth Rinse in Exercise Performance of Fit Athletes in 11 participants. Completed in 17 May 2025.
15 May 2025
Quick facts
| Lead sponsor | CHA University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 11 |
| Start date | 28 February 2025 |
| Primary completion | 15 May 2025 |
| Estimated completion | 17 May 2025 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Carbohydrate Mouth Rinse
- Placebo Mouth Rinse
- Music Listening
Conditions studied
- Exercise Performance of Fit Athletes — all drugs for Exercise Performance of Fit Athletes →
Sponsor
CHA University
Who can join
Adults 20 to 30, any sex, with Exercise Performance of Fit Athletes. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates whether rinsing the mouth with a carbohydrate solution can improve brain oxygenation and cognitive function during high-intensity exercise. Eleven trained cyclists participated in multiple exercise sessions under different mouth rinse conditions. Brain oxygenation, perceived exertion, and cognitive performance were measured. The goal is to understand if this simple technique can support both physical and mental performance during demanding exercise.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Oral carbohydrate sensing enhances prefrontal cortex oxygenation, reduces perceived exertion, and improves high-intensity cycling performance: A randomized crossover trial.
Park SB, Oh K, Yang G, Kim T, et al · · 2026 · PMID 42118778 · DOI 10.1371/journal.pone.0349067
Verify or expand the search:
- PubMed search for NCT07099807
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Carbohydrate Mouth Rinse
Trials testing the same drug.
- NCT06742398 — Carbohydrates and Running Performance · NA · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07099807 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by CHA University
- Last refreshed: 1 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07099807.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing