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NCT07096375
Coupling of IPACK Block With Adductor Canal Block Versus Adductor Canal Block Alone on Pain, Functional Recovery and Inflammatory Response After Knee Replacement
NA trial testing Adductor Canal Block (ACB) + iPACK Block in Adductor Canal Block in 50 participants. Not yet recruiting.
28 June 2026
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 50 |
| Start date | 20 September 2025 |
| Primary completion | 28 June 2026 |
| Estimated completion | 28 September 2026 |
Drugs / interventions tested
- Adductor Canal Block (ACB) + iPACK Block — full drug profile →
- Adductor Canal Block (ACB) + iPACK Block (sham injection)
Conditions studied
- Adductor Canal Block — all drugs for Adductor Canal Block →
- Total Knee Replacement Surgery — all drugs for Total Knee Replacement Surgery →
- Functional Recovery — all drugs for Functional Recovery →
Sponsor
Ain Shams University
Who can join
Adults 20 to 70, any sex, with Adductor Canal Block or Total Knee Replacement Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to compare the Competency of coupling of IPACK Block with Adductor Canal Block versus Adductor Canal Block Alone on Postoperative Pain after total knee replacement as well as Functional Recovery and Inflammatory Response and range of motion postoperatively.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07096375
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Adductor Canal Block (ACB) + iPACK Block
Trials testing the same drug.
- NCT07324486 — Postoperative Analgesic Efficacy Between Adductor Canal Block + IPACK Block and Adductor Canal Block + Genicular Nerve B · NA · not yet recruiting
- NCT06783712 — Comparative Study Between Ultrasound-Guided IPACK Block (Interspace Between the Popliteal Artery and the Posterior Capsu · Phase 1 · unknown
- NCT05498870 — iPACK for Post-op Pain Following ACL Reconstruction · Phase 4 · completed
Other recruiting trials for Adductor Canal Block
Currently open trials in the same condition.
- NCT07082374 — Dual Subsartorial Versus Adductor Canal Block Versus Femoral Nerve Block for Postoperative Analgesia in Patients Undergo · NA · recruiting
- NCT06837844 — Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty · NA · recruiting
- NCT05981105 — Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty · NA · recruiting
- NCT05518513 — Continuous Infusion and Intermittent Bolus Adductor Canal Block for Total Knee Arthroplasty · NA · recruiting
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07096375 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 31 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07096375.
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